Newly learned information should be fresh in your mind in a normally functioning brain, but Alzheimer’s disease robs people of the ability to even recall things that they just learned. Most often, it is friends or family members who begin to be concerned about signs of memory loss in a loved one, and they are the ones who then become responsible for getting help for the person who is going through dementia.
The Alzheimer’s Association says ‘As Alzheimer’s advances through the brain it leads to increasingly severe symptoms, including disorientation, mood and behavior changes; deepening confusion about events, time and place; unfounded suspicions about family, friends and professional caregivers; more serious memory loss and behavior changes; and difficulty speaking, swallowing and walking.’
RESEARCH ON THE USE OF MARIJUANA TO CURE COGNITIVE DISORDERS LIKE ALZHEIMER’S DISEASE
Alzheimer’s disease may be in part caused by the accumulation of proteins on neurons. Beta amyloid is one of these proteins that can increase in the brain as we age. The natural medical miracle of marijuana may be the key, according to these research discoveries, to curing Alzheimer’s disease.
Researchers at the Cellular Neurobiology Laboratory at The Salk Institute for Biological Studies, in La Jolla, CA say that intracellular beta amyloid initiates a toxic inflammatory response that leads to cell death in the brain. Both cannabinoids that are psychoactive, like the THC in cannabis that gets you high, and the non-psychoactive canninoid compounds, like CBD, stimulate the removal of beta amyloid, block the inflammatory response, and are protective.
The data from the study showed that there is an inflammatory response within nerve cells that is caused by the accumulation of intracellular beta amyloid proteins. This protein accumulation in nerve cells leads to early onset Alzheimer’s disease, and the progression of the disease can be cured by stimulating the cannabinoid receptors of the brain.
The researchers at The Salk Institute for Biological Studies concluded by saying that ‘Cell death can only be completely prevented by 5-LOX inhibitors, cannabinoids and caspase inhibitors. However, once the cell death process is underway, death can be reduced by some prostaglandins.’
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A research study by the Endocannabinoid Research Group, Institute of Biomolecular Chemistry based in Naples, Italy that reviewed the previous research on cannabis receptors in the brain found that ‘the available data indicate that endocannabinoids are likely to play in this disor- der a role similar to that suggested in other neurodegenerative diseases, that is, to represent an endogenous adaptive re- sponse aimed at counteracting both the neurochemical and inflammatory consequences of -amyloid-induced tau protein hyperactivity, possibly the most important underlying cause of AD.
Furthermore, plant and synthetic cannabinoids, and particularly the non-psychotropic cannabidiol, might also exert other, non-cannabinoid receptor-mediated protective ef- fects, including, but not limited to, anti-oxidant actions. There is evidence, from in vivo studies on -amyloid-induced neurotoxicity, also for a possible causative role of endocannabinoids in the impairment in memory retention, which is typical of AD. This might open the way to the use of cannabinoid receptor antagonists as therapeutic drugs for the treat- ment of cognitive deficits in the more advanced phases of this disorder.’
MEDICAL MARIJUANA AND ALZHEIMER’S DISEASE
Many states have approved the use of medical marijuana for certain debilitating conditions. Medical use of cannabis is approved for Alzheimer’s disease therapy in several states where medical marijuana use has been approved by the state. A Google search for your state’s approved medical conditions for cannabis use will help you find out if this natural medical miracle can help you or your loved ones to relieve some of the progression of Alzheimer’s disease.